jesse_the_k: Human in professorial suit but with head of Golden Retriever, labeled "Woof" (doctor dog to you)
[personal profile] jesse_the_k
Thanks to [personal profile] shehasathree for linking to this fascinating (if depressing) article about the unfulfilled promise of evidence based medicine.

http://retractionwatch.com/2016/03/16/evidence-based-medicine-has-been-hijacked-a-confession-from-john-ioannidis/

begin quote
Since clinical research that can generate useful clinical evidence has fallen off the radar screen of many/most public funders, it is largely left up to the industry to support it. The sales and marketing departments in most companies are more powerful than their R&D departments. Hence, the design, conduct, reporting, and dissemination of this clinical evidence becomes an advertisement tool. As for “basic” research, as I explain in the paper, the current system favors PIs who make a primary focus of their career how to absorb more money. Success in obtaining (more) funding in a fiercely competitive world is what counts the most. Given that much “basic” research is justifiably unpredictable in terms of its yield, we are encouraging aggressive gamblers. Unfortunately, it is not gambling for getting major, high-risk discoveries (which would have been nice), it is gambling for simply getting more money.
end quote


The speaker is John Ioannidis, heavily cited for his paper,

"Why Most Published Research Findings Are False"
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182327/

(no subject)

Date: 2017-04-16 09:53 pm (UTC)
firecat: red panda looking happy (Default)
From: [personal profile] firecat
Sadly he's probably right. The more I drill down into medical studies the more problems I find.

(no subject)

Date: 2017-04-17 07:01 pm (UTC)
bibliofile: Fan & papers in a stack (from my own photo) (Default)
From: [personal profile] bibliofile
I'm hoping it's not just confirmation bias that I seem to agree with his premise. And the Republicans are not going to help improve things AT ALL.

(no subject)

Date: 2017-04-22 02:03 pm (UTC)
luzula: a Luzula pilosa, or hairy wood-rush (Default)
From: [personal profile] luzula
Interesting, thank you!

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jesse_the_k: mirror reflection of 1/3 of my head, creating a central third eye, a heart shaped face, and a super-pucker mouth (Default)
Jesse the K

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